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Sensiq Technologies pioneer optical biosensor
Pioneer Optical Biosensor, supplied by Sensiq Technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pioneer+optical+biosensor/pioneer+optical+biosensor/us11787768-1599-21-24
Average 90 stars, based on 1 article reviews
pioneer optical biosensor - by Bioz Stars, 2026-10
90/100 stars

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Related Articles

SPR Assay:

Article Title: Alteration of RNA splicing by small molecule inhibitors of the interaction between NHP2L1 and U4
Article Snippet: .. SPR experiments were performed at 20° C on a SensiQ Pioneer optical biosensor (SensiQ Technologies). .. Neutravidin (Thermo Scientific) was immobilized on carboxylated polysaccharide-coated gold chips (COOH5 chips; SensiQ Technologies) by routine amine coupling chemistry in immobilization buffer (10 mM HEPES pH 7.4, 150 mM NaCl, 0.005% Tween20).

Article Title: HDL is the primary transporter for carotenoids from liver to retinal pigment epithelium in transgenic ApoA-I -/- /Bco2 -/- mice.
Article Snippet: Supplementation with antioxidant carotenoids is a therapeutic strategy to protect against age-related macular degeneration (AMD); however, the transport mechanism of carotenoids from the liver to the retina is still not fully understood.. Here, we investigate if HDL serves as the primary transporter for the macular carotenoids.. ApoA-I, the key apolipoprotein of HDL, was genetically deleted from BCO2 knockout (Bco2 /− ) mice, a macular pigment mouse model capable of accumulating carotenoids in the retina.

Article Title: Mechanism for the selective uptake of macular carotenoids mediated by the HDL cholesterol receptor SR-BI
Article Snippet: The macular carotenoids lutein and zeaxanthin are taken up from the bloodstream into the human retina through a selective process, for which the HDL cholesterol receptor scavenger receptor BI (SR-BI) in the cells of retinal pigment epithelium (RPE) is thought to be a key mediator.. However, the mechanism of SR-BI-mediated selective uptake of macular carotenoids is still not fully understood.. Here, we investigate possible mechanisms using biological assays and cultured HEK293 cells, a cell line without endogenous SR-BI expression.

Article Title: Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors
Article Snippet: The Protonate 3D module 47 in the MOE application (v2016.08, Chemical Computing Group) was used to assign ionization states and to position hydrogens (rotamers and tautomers). .. SPR experiments were conducted at 15° C using a SensiQ Pioneer optical biosensor (SensiQ Technologies). .. Poly-His tagged BRD2 constructs were immobilized on polycarboxylate-coated gold chips preimmobilized with nitrilotriacetic acid (His-Cap chips; SensiQ Technologies) by capture-coupling, a hybrid method of capture and amine coupling chemistry 49 .

Article Title: Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors
Article Snippet: .. Binding by Surface Plasmon Resonance (SPR) SPR experiments were conducted at 15° C using a SensiQ Pioneer optical biosensor (SensiQ Technologies). .. Poly-His tagged BRD2 constructs were immobilized on polycarboxylate-coated gold chips preimmobilized with nitrilotriacetic acid (His-Cap chips; SensiQ Technologies) by capture-coupling, a hybrid method of capture and amine coupling chemistry 49 .

Article Title: Tetrahydroquinoline-based bromodomain inhibitors
Article Snippet: .. Surface Plasmon Resonance (Biacore) Analysis of Binding to BRD2-BD1 and BRD2-BD2 SPR experiments were conducted at 15° C. using a SensiQ Pioneer optical biosensor (SensiQ Technologies). .. Surface Plasmon Resonance (Biacore) Analysis of Binding to BRD2-BD1 and BRD2-BD2 SPR experiments were conducted at 15° C. using a SensiQ Pioneer optical biosensor (SensiQ Technologies).

Spectroscopy:

Article Title: HDL is the primary transporter for carotenoids from liver to retinal pigment epithelium in transgenic ApoA-I -/- /Bco2 -/- mice.
Article Snippet: Supplementation with antioxidant carotenoids is a therapeutic strategy to protect against age-related macular degeneration (AMD); however, the transport mechanism of carotenoids from the liver to the retina is still not fully understood.. Here, we investigate if HDL serves as the primary transporter for the macular carotenoids.. ApoA-I, the key apolipoprotein of HDL, was genetically deleted from BCO2 knockout (Bco2 /− ) mice, a macular pigment mouse model capable of accumulating carotenoids in the retina.

Article Title: Mechanism for the selective uptake of macular carotenoids mediated by the HDL cholesterol receptor SR-BI
Article Snippet: The macular carotenoids lutein and zeaxanthin are taken up from the bloodstream into the human retina through a selective process, for which the HDL cholesterol receptor scavenger receptor BI (SR-BI) in the cells of retinal pigment epithelium (RPE) is thought to be a key mediator.. However, the mechanism of SR-BI-mediated selective uptake of macular carotenoids is still not fully understood.. Here, we investigate possible mechanisms using biological assays and cultured HEK293 cells, a cell line without endogenous SR-BI expression.

Modification:

Article Title: HDL is the primary transporter for carotenoids from liver to retinal pigment epithelium in transgenic ApoA-I -/- /Bco2 -/- mice.
Article Snippet: Supplementation with antioxidant carotenoids is a therapeutic strategy to protect against age-related macular degeneration (AMD); however, the transport mechanism of carotenoids from the liver to the retina is still not fully understood.. Here, we investigate if HDL serves as the primary transporter for the macular carotenoids.. ApoA-I, the key apolipoprotein of HDL, was genetically deleted from BCO2 knockout (Bco2 /− ) mice, a macular pigment mouse model capable of accumulating carotenoids in the retina.

Binding Assay:

Article Title: Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors
Article Snippet: .. Binding by Surface Plasmon Resonance (SPR) SPR experiments were conducted at 15° C using a SensiQ Pioneer optical biosensor (SensiQ Technologies). .. Poly-His tagged BRD2 constructs were immobilized on polycarboxylate-coated gold chips preimmobilized with nitrilotriacetic acid (His-Cap chips; SensiQ Technologies) by capture-coupling, a hybrid method of capture and amine coupling chemistry 49 .

Article Title: Tetrahydroquinoline-based bromodomain inhibitors
Article Snippet: .. Surface Plasmon Resonance (Biacore) Analysis of Binding to BRD2-BD1 and BRD2-BD2 SPR experiments were conducted at 15° C. using a SensiQ Pioneer optical biosensor (SensiQ Technologies). .. Surface Plasmon Resonance (Biacore) Analysis of Binding to BRD2-BD1 and BRD2-BD2 SPR experiments were conducted at 15° C. using a SensiQ Pioneer optical biosensor (SensiQ Technologies).



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